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R-4106A

(410 Sexy)

Lower-TFA Alternative to R-454B

Save $100 Per Jug*

EPA SNAP approved for new equipment; retrofit pending. A2L for equipment. Non-flammable for transport and storage.

Find a wholesaler (coming soon)

*Estimated savings; compared to current market price.

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DOT Non-Flammable
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Direct alternative to R-454B
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~90% less TFA than R-454B

R-4106A

FluoroFusion Introduces R-4106A (410 Sexy)

R-4106A is FluoroFusion's patented A2L refrigerant blend, engineered as a direct alternative to R-454B and sold under the Arctic Eagle® brand. It is EPA SNAP approved for new equipment. Retrofit approval is pending.

 

Performance vs. R-454B

Thermodynamic cycle analysis, NIST REFPROP v10, nine operating conditions (evaporator −25 °F to 130 °F):

  • Cooling capacity: +6.6% average (range +5.0% to +8.5%), modeled

  • Efficiency (COP): +2.7% average (range +1.4% to +3.9%), modeled

  • TFA formation: roughly a 90% reduction versus R-454B

 

The Compliance & Safety Advantage

R-4106A has a blend GWP of 681 (40 CFR 84.64), below the 700 GWP limit for new residential and light commercial A/C and heat pump systems. For equipment application it carries the same ASHRAE A2L classification as R-454B. For transport and storage it is classified non-flammable under DOT, OSHA, NFPA and NEC, so it isn't subject to flammable-goods limits on truck stock or in-facility storage.

 

Why Choose R-4106A?

  • Carry more, store more: DOT non-flammable for transport and storage

  • GWP is one number. R-4106A is designed around what a refrigerant turns into, with roughly 90% less TFA formation than R-454B

  • Made in NC USA with global components: manufactured in Clayton, North Carolina, for supply security

  • Circular economy: net GWP below 10 on a production/allocation consumption basis when formulated from reclaimed components

  • POE lubricant. Zeotropic blend: charge in the liquid phase

  • Covered by U.S. Patent 12,540,265 B2; presented at the 21st International Refrigeration and Air Conditioning Conference at Purdue, July 2026

 

The Numbers on R-4106A vs. R-454B
Head-to-head data across capacity, efficiency, glide, discharge pressure, LFL, TFA formation, DOT classification, and price. Every OEM objection answered point by point, with sources. Four pages.

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R-4106A Retrofit Guide

Download the step-by-step R-4106A retrofit guide. R-4106A is EPA SNAP approved for new equipment; retrofit approval is pending.

Contact us

Notify me when R-4106A is available

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Case Study Questionnaire

Objective: To collect comprehensive data regarding the replacement of R-454B with FluoroFusion's proprietary refrigerant R-4106A.
Both R-454B and R-4106A are A2L (mildly flammable) refrigerants. This data will be used by FluoroFusion to develop a detailed,
factual case study comparing system performance between the two refrigerants.

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R-4106A SDS

Download and view the Safety Data Sheet for R-4106A

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